Digital Experience Program

Thank you for your interest in the AMP 2021 Digital Experience!

The AMP 2021 Program Committee has been working hard to plan a comprehensive program, which will have a number of Virtual Corporate Workshops, Selected Scientific Presentations and Networking Opportunities.  Please check the Registration Page for more information about what is included in the different registration options.

Please note: all times are Eastern Standard Time (EST).

Digital Experience Program:

Be sure to check back for updated Program information often!

Quick Links

Monday

Tuesday

Wednesday

Thursday

Friday

On Demand

 

Monday, November 15, 2021

12:00pm - 1:30pm

Independent Satellite Symposia: The Molecular Pathologist’s Role in Gene Fusion Testing for Thyroid Cancer

Developed through a partnership between Medscape Oncology and the Association for Molecular Pathology

 

Tuesday, November 16, 2021

9:00am - 9:50am

LIVE Corporate Workshop presented by PGDx

10:30am - 11:20am

LIVE Corporate Workshop presented by Canexia Health

12:00pm - 1:00pm

At the Intersection of Precision Medicine and Machine Learning 

Eliezer Van Allen, MD, Dana Farber Cancer Institute, Brookline, MA, USA

1:30pm - 2:20pm

LIVE Corporate Workshop presented by AstraZeneca

3:00pm - 3:50pm

LIVE Corporate Workshop presented by 10x Genomics

4:15pm - 5:15pm

MRD for Lymphoma Beyond Immunoglobulin

Ash Alizadeh, MD, PhD, Color Health, Stanford, CA, USA

 

Wednesday, November 17, 2021

9:00am - 9:50am

LIVE Corporate Workshop presented by Mission Bio

10:30am - 11:20am

LIVE Corporate Workshop 

12:00pm - 1:00pm

How Far are We from an HIV Cure?  Implications for Molecular Diagnostics 

Pathways Towards an HIV Cure? Implications for Molecular Diagnostics

Deborah Persaud, MD, Johns Hopkins University School of Medicine, Baltimore, MD, USA

1:30pm - 2:20pm

LIVE Corporate Workshop presented by NanoString

3:00pm - 3:50pm

LIVE Corporate Workshop presented by Adaptive Biotechnologies Corp.

4:15pm - 5:45pm

The Changing Landscape of Reimbursement for Pathology Clinical Consultation and Impact on Interpretation of Tumor Genomics

Coding and Reimbursement for Tumor Profiling Interpretation, Clinical Correlation and Consultation

Samuel K. Caughron, MD, MAWD Pathology Group, Lenexa, KS, USA

Demystifying Molecular Diagnostics Coverage and Reimbursement in Medicare: MolDX

Gabriel Bien-Willner, MD, PhD, Palmetto GBA, TX, USA

 

Thursday, November 18, 2021

9:00am - 9:50am

LIVE Corporate Workshop presented by Bionano Genomics

10:30am - 11:20am

LIVE Corporate Workshop presented by Karius

12:00pm - 1:00pm

AMP Award for Excellence in Molecular Diagnostics: Presentation and Lecture

CRISPRology: Science and Ethics of Genome Editing

Jennifer Doudna, PhD, University of California, Berkeley, CA, USA

1:30pm - 2:20pm

LIVE Corporate Workshop presented by Asuragen

3:00pm - 3:50pm

LIVE Corporate Workshop presented by Illumina

4:15pm - 5:45pm

Applications of Therapeutic Gene Editing 

Development and Application of Genome Editing Technologies

Fyodor Urnov, PhD, University of California, Berkeley, CA, USA

Gene Editing for the Treatment of Red Blood Cell Disorders

Haydar Frangoul, MD, Sarah Cannon Center for Blood Cancer, Nashville, TN, USA

 

Friday, November 19, 2021

9:00am - 9:50am

LIVE Corporate Workshop

10:30am - 11:20am

LIVE Corporate Workshop presented by Eli Lilly

12:00pm - 1:00pm

The Origins of Gene Amplifications in Cancer 

Characterizing somatic mutations in non-cancerous cells

Peter J. Park, PhD, Harvard Medical School, Boston, MA, USA

1:30pm - 2:20pm

LIVE Corporate Workshop presented by Roche

3:00pm - 3:50pm

LIVE Corporate Workshop

4:15pm - 5:15pm

Networking Event

 

On Demand Sessions available January 2022

On Demand

PLENARY SESSIONS

Advances in Clinical Applications for Complex Genetic Disorders 

On Demand

SYMPOSIA SESSIONS

New Insights into Cancer Biology from DNA Mutational Signatures

The Repertoire of Mutational Signatures in Human Cancer

Ludmil B. Alexandrov, PhD, University of California San Diego, La Jolla, CA, USA

Ongoing efforts to identify causes of currently unexplained signatures

Serena Nik-Zainal, MD, PhD, University of Cambridge, Cambridge, United Kingdom

Liquid Biopsy and MRD

Use of Patient Specific Panels for MRD Detection

Viktor Adalsteinsson, PhD, Broad Institute of MIT and Harvard, Wakefield, MA, USA

New Applications of CAR T-Cells

CAR T-cell therapies for autoimmune diseases

Michael Milone

“Mechanisms of CAR T cells”

Macela Maus, MD, PhD, Massachusetts General Hospital East, Charlestown, MA, USA

Practical Issues with Quantitative Molecular Testing for Infectious Diseases

Validation of Samples Shared Between Molecular and Other Testing Platforms

Rebecca Harris, University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, PA, USA

CMV Viral Load Testing

Randall Hayden, MD, St. Jude Children's Research Hospital, Memphis, TN, USA

Practical Considerations to Optimize Algorithmic Testing for the Diagnosis of HIV

Blake W. Buchan, PhD, Medical College of Wisconsin, Milwaukee, WI, USA

On Demand

BREAKOUT SESSIONS

Low Coverage Whole Genome Sequencing

Low-pass Genome Sequencing and Polygenic Risk Scores

Joe Pickrell, Gencove, New York, NY, USA

Low Coverage Whole Genome Sequencing

Julian Homburger, PhD, Color Health, Alamo, CA, USA

Alternative Perspectives to Multi-omics Single-cell Analysis

Alternative Perspectives to Multi-omics Single-cell Analysis

Robert B. Faryabi, PhD, MSc, University of Pennsylvania School of Medicine, Philadelphia, PA, USA

 

Tracking the Global Spread of Mutli-Drug Resistant Organisms

The Genomics, Evolution, and Spread of Drug-resistant Neisseria gonorrhoeae

Yonatan Grad, MD, PhD, Harvard Chan School of Public Health, Boston, MA, USA

Tracking the Global Spread of Mutli-Drug Resistant Organisms

Paul J. Planet, MD, PhD, University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, PA, USA

New Developments in Mitochondrial DNA Variant Identification and Classification 

Mitochondrial DNA Variant Classification and MITOMAP

Marni J. Falk, MD, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Promises & Pitfalls of EHR-based Variant Reanalysis 

Variant Reclassification and Reinterpretation - Challenges and Opportunities in Current and Future EHR Usability and Function

Alexis Carter, MD, Children’s Healthcare of Atlanta, Atlanta, GA, USA

Improvement and Challenges of EHR System and Integration of Genomic Data

Alexis Carter, MD, Children’s Healthcare of Atlanta, Atlanta, GA, USA

Considerations for the Optimal Detection of Clinically Relevant Fusions in Solid Tumors 

Overview of the Various Methodologies for Fusion Detection in a Clinical Laboratory

John Iafrate, MD, PhD, Massachusetts General Hospital, Boston, MA, USA

Clinical Fusion Detection Approaches and Methodologies

Susan Hsiao, MD, PhD, Columbia University Medical Center, New York, NY, USA

Genetic Healthcare Disparities

Social Implications of Genetic Diagnosis and Therapies

John Carpten, PhD, University of Southern California, Los Angeles, CA, USA

Enabling Precision Medicine for Diverse Populations

Lucia Hindorff, PhD, MPH, National Human Genome Research Institute, Bethesda, MD, USA

Lack of Diversity in Genomics and Implications for Clinical Genetics

Alice B. Popejoy, PhD, University of California, Davis, Sacramento, CA, USA

Molecular Diagnostics in the Community Hospital: How to Offer Complete and Up to Date Testing

Overview of Provision and Utilization of Molecular Testing in Community Cancer Centers, Ideally from an Individual Involved in the Association of Community Cancer Centers

Tabetha Sundin, PhD, HCLD (ABB), MB (ASCP)CM, AstraZeneca, Middletown, MD, USA

Experience from Molecular Pathologists Running Laboratories in a Community or Non-academic Setting, Discussing How They've Chosen What Types of Molecular Testing to Provide and How They Have Established Their Role in the Larger Molecular Laboratory Ecosystem

Michelle Shiller, DO, AP/CP, MGP, Baylor Scott & White Health, Dallas, TX, USA

Novel Insights into Clonal Hematopoiesis

Link Between Cancer Therapy and Clonal Hematopoiesis

Ahmet Zehir, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Rationale for screening stem cell donors for clonal hematopoiesis

Lukasz Gondek, MD, PhD, Johns Hopkins School of Medicine, Ellicott City, MD, USA

Rationale for not screening stem cell donors for clonal hematopoiesis

Coleman Lindsley, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, USA

Pharmacogenomic Testing Across Populations 

Pharmacogenomics Implementation Across Populations in North America

Deepak Voora, MD, Duke University, Durham, NC, USA

Implementation of Pharmacogenetics in Clinical Care: an EU perspective

Ron HN Van Schaik, PhD, Erasmus MC, Rotterdam, Zuid-Holland, Netherlands

Pharmacogenomics in Pediatrics

Laura B. Ramsey, PhD, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA

Cool New Tech for At-Home Testing

Rapid, Point-of-Care Diagnostics

Nira Pollock

Cool New Tech for At-Home Testing

Jonathan Posner

Cool New Tech for At-Home Testing

Melanie Ott, MD, PhD, Gladstone Institute of Virology and UCSF, San Francisco, CA, USA

On Demand

TARGETED TOPICS

Perspectives on Tumor Mutational Burden: An Update from the AMP TMB Working Group

Larissa V. Furtado, MD, St. Jude Children’s Research Hospital, Memphis, TN, USA

Lauren Ritterhouse, MD, PhD, Massachusetts General Hospital, Andover, MA, USA

Utilization of NGS Testing in Cytopathology Samples

Hamza N. Gokozan, MD, Weill Cornell Medicine, New York, NY, USA

Mitochondrial DNA as Clonal Markers to Infer and Track Clonal Mosaicism 

Vijay G. Sankaran, MD, PhD, Boston Children's Hospital/ Harvard Medical School, Boston, MA, USA

Difficult to Sequence Regions in the Genome 

Description of Hard to Sequence Regions

Justin M. Zook, PhD, NIST, Gaithersburg, MD, USA

Informatics Solutions to Difficult to Sequence Regions

Karen Miga, PhD, University of California, Santa Cruz, CA, USA

Advanced Sequencing Applications in the Public Health Laboratory

Molecular Streptococcus Pneumoniae Serotyping

Sara Vetter, PhD, D(ABMM), Minnesota State Public Health Laboratory, St. Paul, MN, USA

How NGS Is Used for Outbreak Detection

Heather Carleton, CDC, Atlanta, GA, USA

On Demand

PLATFORM PRESENTATIONS

Platform Presentations of Selected Abstracts

Abstracts are selected by the Program Committee

Platform Presentations of Selected Genetics Abstracts

G04 - A Comparison of Strategies for the Collection and Use of Phenotypic Information in the North Carolina Clinical Genomic Evaluation by Next-Generation Exome Sequencing 2 (NCGENES 2) Study

Shannon McNulty, University of North Carolina at Chapel Hill, Durham, NC, USA

G28 - Implementing a Genomic Population Health Screening Program in Primary Care: Lessons Learned

Robert Wildin, MD, University of Vermont Larner College of Medicine, Burlington, VT, USA

G23 - COVID19 symptoms vary by HLA haplogroup in a well typed crowd cohort

Jeffrey Rosenfeld, PhD, Rutgers University, New Brunswick, NJ, USA

G01 - A Novel Machine Learning Plus Whole Methylome Approach for the Diagnosis of Germline Disorders

Linda Hasadsri, MD, PhD, Mayo Clinic, Rochester, MN, USA

Platform Presentations of Selected Hematopathology Abstracts

H27 - Comprehensive Genomic Profiling Discovers Recurrent Mutations and Copy Number Alterations of T-cell Large granular Lymphocytic Leukemia

Jinjuan Yao, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, USA

H19 - Clonal cytogenetic abnormalities in donor-derived cells after sex mismatched allogenic stem cell transplantation

Gokce Toruner, MD, PhD, UT MD Anderson Cancer Center, Houston, TX, USA

H22 - Clinicopathologic Features of Acute Myeloid Leukemia with NUP98 Rearrangement

Maria Magallanes Hoyos, Oregon Health and Science University

H20 - AML with germline DDX41 mutations is a distinct clinicopathologically and molecularly defined entity with a sub-acute course and favorable outcome

Margaret C. Williams, MD, University of Utah/ARUP Labs, Salt Lake City, UT, USA

Platform Presentations of Selected Infectious Diseases Abstracts

ID20 - Development and Six-Month Evaluation of SARS-CoV-2 Wastewater Surveillance in a Low-Prevalence Rural Region (The RECOVER Project)

Diana Toledo, PhD, MS, GSC, The Broad Institute of MIT and Harvard, Cambridge, MA, USA

ID06 - Genetic variation in circulating SARS-CoV-2 is detected by RT-PCR/MALDI-TOF diagnostic targets

Matthew Hernandez, MD, PhD, Icahn School of Medicine at Mount Sinai, New York, NY  USA

ID24 - Fragment Analysis for Scalable Detection of SARS-CoV-2 Variants of Concern

Jeffrey SoRelle, MD, UT Southwestern University, Dallas, TX, USA

Platform Presentations of Selected Informatics Abstracts

I04 - CNViz: an R/Shiny Application For Interactive Copy Number Variant Visualization in Cancer

Rebecca Greenblatt, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

I08 - CloneSeer: Sequence Alignment-Based Detection and Quantification of Lymphoma Sub-Clones

Eitan Halper-Stromberg, MD, PhD, Johns Hopkins University, Baltimore, MD, USA

I13 - UNISON: A UNIfied SOmatic CalliNg (UNISON) pipeline for identifying Clonal Hematopoiesis of Indeterminate Potential

Eric Klee, Mayo Clinic, Rochester, MN, USA

I02 - Human Leukocyte Antigen Typing of Patients with Myeloid Malignancies by Whole Genome Sequencing

Andrew Hughes, Washington University School of Medicine, St. Louis, MS, USA

Platform Presentations of Selected Solid Tumors Abstracts

ST71 - Targeted next-generation sequencing of biliary tract specimens from patients with primary sclerosing cholangitis improves the early detection of cholangiocarcinoma

Jeffrey Kleinberger, MD, PhD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

ST08 - PurIST Pancreatic Cancer Classifier: A 16-RNA Expression Signature Array Comparable to RNAseq

Margaret Gulley, MD, University of NC, Chapel Hill, NC, USA

ST74 - Optical genome mapping for the chromosomal characterization of solid tumors

Ravindra Kolhe, MD, PhD, FCAP, Augusta University, Augusta, GA, USA

ST57 - Translating Transcriptome Sequencing into Clinical Diagnostics for Pediatric Solid Tumors

Feng Xu, PhD, Children's Hospital of Philadelphia, Philadelphia, PA, USA

Platform Presentations of Selected Technical Topics Abstracts

TT34 - Qualitative Detection of EGFR mutations (exons 18–21) in Lung cancer using Idylla Platform

Meenakshi Mehrotra, PhD, Icahn School of Medicine, New York, NY, USA

TT25 - Urine-Based Testing for Mitochondrial Diseases: An Alternative to Invasive Muscle Biopsies?

Taylor Ashworth, MLS(ASCP), Mayo Clinic, Apple Valley, MN, USA

TT12 - Validation of Targeted Next-Generation Sequencing of Cell-Free DNA from Stored Cerebrospinal Fluid Specimens for the Detection of Somatic Variants in Cancer Involving the Leptomeninges

Alexander Neil, MD, PhD, Brigham and Women's Hopsital, Boston, MA, USA

On Demand

CASE STUDIES

Case Studies in Genetics

Sebaceous Adenoma of the Penis Suspicious for Muir-Torre Syndrome

Blaire Anderson, Geisel School of Medicine at Dartmouth/Dartmouth Hitchcock Medical Center, Quechee, VT, USA

Molecular Diagnosis of a Patient with a Novel Suspected Hereditary Amyloidosis

Lauren Choate, PhD, Mayo Clinic, Rochester, MN, USA

A case of familial cytopenias and cerebral cavernous malformations presenting with seizures and brain abscesses

Runjun Kumar, MD, PhD, Baylor College of Medicine, Houston, TX, USA

Case Studies in Hematopathology

Molecular and histopathologic findings in a case of large B-cell lymphoma with IRF4 rearrangement

Farah El-Sharkway, MD, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

A Genetically Novel Mantle Cell Lymphoma

Ahmed Lazim, Temple University Hospital, Philadelphia, PA, USA

Incidental discovery of acute myeloid leukemia during liquid biopsy of a lung cancer patient

Dingani Nkosi, PhD, University of Rochester Medical Center, Rochester, NY, USA

Inadvertent allogeneic hematopoietic stem cell transplant from a lung allograft

Laura Schultz-Rogers, PhD, University of North Carolina Chapel Hill Hospital, Chapel Hill, NC, USA

Clinical Whole Genome Sequencing Characterizes an Unusual Case of B-lymphoblastic Leukemia/Lymphoma

Brooj Abro, Washington University in St. Louis, St. Louis, MS, USA

Clonally Related Marginal Zone Lymphoma and Classic Hodgkin Lymphoma: A Rare Case Highlighting the Importance of IGK Rearrangement Testing

Bradley Drumheller, MD, Emory University Hospital, Atlanta, GA, USA

Case Studies in Infectious Diseases

Even if it looks like a ductal and walks like a ductal. . .

Jeremy Adler, University of  Chicago, Chicago, IL, USA

Case Studies in Solid Tumors

A rare case of CIC-rearranged sarcoma diagnosed with integrated RNA and DNA sequencing

Annie Garcia, MD, Baylor College of Medicine, Houston, TX, USA

Identification of identical BAP1 mutations in a patient’s peritoneal mesothelioma and mucosal melanoma: A precision medicine case study

Paul Zamiara, MD, Dalhousie University, Halifax, Nova Scotia, Canada

Clonal Evolution of Glioblastoma after Therapy

Tasos Gogakos, Mass General/Brigham Womens, Boston, MA, USA

A case series of FGFR3-KLF15 Fusion in Non-Small Cell Lung Cancer

Parsa Hodjat, Houston Methodist Hospital, Houston, TX, USA

Potentially Targetable FGFR2-INA Fusion in Intraductal Tubulopapillary Neoplasm of Pancreas (ITPN)

Irena Manukyan, Columbia University, Bethesda, MD, USA

Detection of a rare fusion event to confirm metastasis and primary

Drew Williamson, Briham and Women's Hospital, Boston, MA, USA