Digital Experience Program

The AMP 2021 Program Committee has worked very hard to plan a comprehensive program.



Digital Experience Program:

The presentations listed below will only be available for Digital Experience - FULL registrants in January 2022 as OnDemand Sessions.

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Plenary Sessions

Symposia Sessions

Breakout Sessions

Targeted Topics

Platform Presentations

Case Studies

On Demand Sessions available January 2022

On Demand


At the Intersection of Precision Medicine and Machine Learning 

Eliezer Van Allen, MD, Dana Farber Cancer Institute, Brookline, MA, USA

Characterizing Somatic Mutations in Non-Cancerous Cells

Peter J. Park, PhD, Harvard Medical School, Boston, MA, USA

Pathways Towards an HIV Cure? Implications for Molecular Diagnostics

Deborah Persaud, MD, Johns Hopkins University School of Medicine, Baltimore, MD, USA

MRD for Lymphoma Beyond Immunoglobulin

Ash Alizadeh, MD, PhD, Color Health, Stanford, CA, USA

On Demand


Applications of Therapeutic Gene Editing 

Development and Application of Genome Editing Technologies

Fyodor Urnov, PhD, University of California, Berkeley, CA, USA

Gene Editing for the Treatment of Red Blood Cell Disorders

Haydar Frangoul, MD, Sarah Cannon Center for Blood Cancer, Nashville, TN, USA

Cool New Tech for At-Home Testing

Rapid, Point-of-Care Diagnostics

Nira Pollock

Amplification-free detection of SARS-CoV-2 with CRISPR and a mobile phone

Melanie Ott, MD, PhD, Gladstone Institute of Virology and UCSF, San Francisco, CA, USA

Genetic Healthcare Disparities

Tumor Heterogeneity and Cancer Health Disparities

John Carpten, PhD, University of Southern California, Los Angeles, CA, USA

Diversity reduces health information disparities and enhances the impact of genomic medicine

Lucia Hindorff, PhD, MPH, National Human Genome Research Institute, Bethesda, MD, USA

Lack of Diversity in Genomics and Implications for Clinical Genetics

Alice B. Popejoy, PhD, University of California, Davis, Sacramento, CA, USA

Liquid Biopsy and MRD

Use of Patient Specific Panels for MRD Detection

Viktor Adalsteinsson, PhD, Broad Institute of MIT and Harvard, Wakefield, MA, USA

Low Coverage Whole Genome Sequencing

Using Low Coverage Whole Genome Sequencing to Assess Genome-wide Variation and Polygenic Scores

Julian Homburger, PhD, Color Health, Alamo, CA, USA

New Applications of CAR T-Cells

CAR T-cell therapies for autoimmune diseases

Michael Milone, MD, PhD, University of Pennsylvania, Philadelphia, PA, USA

“Mechanisms of CAR T cells”

Macela Maus, MD, PhD, Massachusetts General Hospital East, Charlestown, MA, USA

New Insights into Cancer Biology from DNA Mutational Signatures

The Repertoire of Mutational Signatures in Human Cancer

Ludmil B. Alexandrov, PhD, University of California San Diego, La Jolla, CA, USA

Ongoing efforts to identify causes of currently unexplained signatures

Serena Nik-Zainal, MD, PhD, University of Cambridge, Cambridge, United Kingdom

Practical Issues with Quantitative Molecular Testing for Infectious Diseases

Current State of HCV Reflex Testing

Rebecca Harris, University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, PA, USA

Challenges in Quantitative CMV Testing and Interpretation

Randall Hayden, MD, St. Jude Children's Research Hospital, Memphis, TN, USA

Practical Considerations to Optimize Algorithmic Testing for the Diagnosis of HIV

Blake W. Buchan, PhD, Medical College of Wisconsin, Milwaukee, WI, USA

On Demand


Alternative Perspectives to Multi-omics Single-cell Analysis

Alternative Perspectives to Multi-omics Single-cell Analysis

Robert B. Faryabi, PhD, MSc, University of Pennsylvania School of Medicine, Philadelphia, PA, USA

Tracking the Global Spread of Mutli-Drug Resistant Organisms

The Genomics, Evolution, and Spread of Drug-resistant Neisseria gonorrhoeae

Yonatan Grad, MD, PhD, Harvard Chan School of Public Health, Boston, MA, USA

Tracking the Global Spread of Mutli-Drug Resistant Organisms

Paul J. Planet, MD, PhD, University of Pennsylvania and Children's Hospital of Philadelphia, Philadelphia, PA, USA

New Developments in Mitochondrial DNA Variant Identification and Classification 

Mitochondrial DNA Variant Classification and MITOMAP

Marni J. Falk, MD, Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA

Mitochondrial DNA Disease and Relationship with Variants

Douglas Wallace, PhD, Children's Hospital of Philadelphia, Philadelphia, PA, USA

Promises & Pitfalls of EHR-based Variant Reanalysis 

Variant Reclassification and Reinterpretation - Challenges and Opportunities in Current and Future EHR Usability and Function

Alexis Carter, MD, Children’s Healthcare of Atlanta, Atlanta, GA, USA

Promises & Pitfalls of EHR-based Variant Reanalysis

Marc Williams, MD, Geisenger Genomic Medicine Institute, Danville, PA, USA

Considerations for the Optimal Detection of Clinically Relevant Fusions in Solid Tumors 

Detection of Gene Fusions in Cancer

John Iafrate, MD, PhD, Massachusetts General Hospital, Boston, MA, USA

Clinical Fusion Detection Approaches and Methodologies

Susan Hsiao, MD, PhD, Columbia University Medical Center, New York, NY, USA

Molecular Diagnostics in the Community Hospital: How to Offer Complete and Up to Date Testing

Overview of Provision and Utilization of Molecular Testing in Community Cancer Centers, Ideally from an Individual Involved in the Association of Community Cancer Centers

Tabetha Sundin, PhD, HCLD (ABB), MB (ASCP)CM, AstraZeneca, Middletown, MD, USA

Guide to Implementing Molecular Testing in a Large Hospital System

Michelle Shiller, DO, AP/CP, MGP, Baylor Scott & White Health, Dallas, TX, USA

Novel Insights into Clonal Hematopoiesis

Link Between Cancer Therapy and Clonal Hematopoiesis

Ahmet Zehir, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Rationale for screening stem cell donors for clonal hematopoiesis

Lukasz Gondek, MD, PhD, Johns Hopkins School of Medicine, Ellicott City, MD, USA

Should stem cell donors be screened for clonal hematopoiesis?

Coleman Lindsley, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, USA

Pharmacogenomic Testing Across Populations 

Pharmacogenomics Implementation Across Populations in North America

Deepak Voora, MD, Duke University, Durham, NC, USA

Implementation of Pharmacogenetics in Clinical Care: an EU perspective

Ron HN Van Schaik, PhD, Erasmus MC, Rotterdam, Zuid-Holland, Netherlands

Pharmacogenomics in Pediatrics

Laura B. Ramsey, PhD, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA

The Changing Landscape of Reimbursement for Pathology Clinical Consultation and Impact on Interpretation of Tumor Genomics

Coding and Reimbursement for Tumor Profiling Interpretation, Clinical Correlation and Consultation

Samuel K. Caughron, MD, MAWD Pathology Group, Lenexa, KS, USA

Demystifying Molecular Diagnostics Coverage and Reimbursement in Medicare: MolDX

Gabriel Bien-Willner, MD, PhD, Palmetto GBA, TX, USA

On Demand


Utilization of NGS Testing in Cytopathology Samples

Hamza N. Gokozan, MD, Weill Cornell Medicine, New York, NY, USA

Mitochondrial DNA as Clonal Markers to Infer and Track Clonal Mosaicism 

Vijay G. Sankaran, MD, PhD, Boston Children's Hospital/ Harvard Medical School, Boston, MA, USA

Difficult to Sequence Regions in the Genome 

Benchmarking variants in challenging medically-relevant genes

Justin M. Zook, PhD, NIST, Gaithersburg, MD, USA

Telomere-to-Telomere Chromosome Assemblies: New Insights Into Genome Biology and Structure

Karen Miga, PhD, University of California, Santa Cruz, CA, USA

Advanced Sequencing Applications in the Public Health Laboratory

Molecular Streptococcus Pneumoniae Serotyping

Sara Vetter, PhD, D(ABMM), Minnesota State Public Health Laboratory, St. Paul, MN, USA

How NGS Is Used for Outbreak Detection

Heather Carleton, CDC, Atlanta, GA, USA

On Demand


Platform Presentations of Selected Abstracts

Abstracts are selected by the Program Committee

Platform Presentations of Selected Genetics Abstracts

G04 - A Comparison of Strategies for the Collection and Use of Phenotypic Information in the North Carolina Clinical Genomic Evaluation by Next-Generation Exome Sequencing 2 (NCGENES 2) Study

Shannon McNulty, University of North Carolina at Chapel Hill, Durham, NC, USA

G28 - Implementing a Genomic Population Health Screening Program in Primary Care: Lessons Learned

Robert Wildin, MD, University of Vermont Larner College of Medicine, Burlington, VT, USA

G01 - A Novel Machine Learning Plus Whole Methylome Approach for the Diagnosis of Germline Disorders

Linda Hasadsri, MD, PhD, Mayo Clinic, Rochester, MN, USA

Platform Presentations of Selected Hematopathology Abstracts

H27 - Comprehensive Genomic Profiling Discovers Recurrent Mutations and Copy Number Alterations of T-cell Large granular Lymphocytic Leukemia

Jinjuan Yao, MD, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, USA

H19 - Clonal cytogenetic abnormalities in donor-derived cells after sex mismatched allogenic stem cell transplantation

Gokce Toruner, MD, PhD, UT MD Anderson Cancer Center, Houston, TX, USA

H22 - Clinicopathologic Features of Acute Myeloid Leukemia with NUP98 Rearrangement

Maria Magallanes Hoyos, Oregon Health and Science University

H20 - AML with germline DDX41 mutations is a distinct clinicopathologically and molecularly defined entity with a sub-acute course and favorable outcome

Margaret C. Williams, MD, University of Utah/ARUP Labs, Salt Lake City, UT, USA

Platform Presentations of Selected Infectious Diseases Abstracts

ID20 - Development and Six-Month Evaluation of SARS-CoV-2 Wastewater Surveillance in a Low-Prevalence Rural Region (The RECOVER Project)

Diana Toledo, PhD, MS, GSC, The Broad Institute of MIT and Harvard, Cambridge, MA, USA

ID06 - Genetic variation in circulating SARS-CoV-2 is detected by RT-PCR/MALDI-TOF diagnostic targets

Matthew Hernandez, MD, PhD, Icahn School of Medicine at Mount Sinai, New York, NY  USA

ID24 - Fragment Analysis for Scalable Detection of SARS-CoV-2 Variants of Concern

Jeffrey SoRelle, MD, UT Southwestern University, Dallas, TX, USA

Platform Presentations of Selected Informatics Abstracts

I04 - CNViz: an R/Shiny Application For Interactive Copy Number Variant Visualization in Cancer

Rebecca Greenblatt, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

I08 - CloneSeer: Sequence Alignment-Based Detection and Quantification of Lymphoma Sub-Clones

Eitan Halper-Stromberg, MD, PhD, Johns Hopkins University, Baltimore, MD, USA

I13 - UNISON: A UNIfied SOmatic CalliNg (UNISON) pipeline for identifying Clonal Hematopoiesis of Indeterminate Potential

Eric Klee, Mayo Clinic, Rochester, MN, USA

I02 - Human Leukocyte Antigen Typing of Patients with Myeloid Malignancies by Whole Genome Sequencing

Andrew Hughes, Washington University School of Medicine, St. Louis, MS, USA

Platform Presentations of Selected Solid Tumors Abstracts

ST71 - Targeted next-generation sequencing of biliary tract specimens from patients with primary sclerosing cholangitis improves the early detection of cholangiocarcinoma

Jeffrey Kleinberger, MD, PhD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

ST08 - PurIST Pancreatic Cancer Classifier: A 16-RNA Expression Signature Array Comparable to RNAseq

Margaret Gulley, MD, University of NC, Chapel Hill, NC, USA

ST74 - Optical genome mapping for the chromosomal characterization of solid tumors

Ravindra Kolhe, MD, PhD, FCAP, Augusta University, Augusta, GA, USA

ST57 - Translating Transcriptome Sequencing into Clinical Diagnostics for Pediatric Solid Tumors

Feng Xu, PhD, Children's Hospital of Philadelphia, Philadelphia, PA, USA

Platform Presentations of Selected Technical Topics Abstracts

TT34 - Qualitative Detection of EGFR mutations (exons 18–21) in Lung cancer using Idylla Platform

Meenakshi Mehrotra, PhD, Icahn School of Medicine, New York, NY, USA

TT25 - Urine-Based Testing for Mitochondrial Diseases: An Alternative to Invasive Muscle Biopsies?

Taylor Ashworth, MLS(ASCP), Mayo Clinic, Apple Valley, MN, USA

TT12 - Validation of Targeted Next-Generation Sequencing of Cell-Free DNA from Stored Cerebrospinal Fluid Specimens for the Detection of Somatic Variants in Cancer Involving the Leptomeninges

Alexander Neil, MD, PhD, Brigham and Women's Hopsital, Boston, MA, USA

On Demand


Case Studies in Genetics

Sebaceous Adenoma of the Penis Suspicious for Muir-Torre Syndrome

Blaire Anderson, Geisel School of Medicine at Dartmouth/Dartmouth Hitchcock Medical Center, Quechee, VT, USA

Molecular Diagnosis of a Patient with a Novel Suspected Hereditary Amyloidosis

Lauren Choate, PhD, Mayo Clinic, Rochester, MN, USA

A case of familial cytopenias and cerebral cavernous malformations presenting with seizures and brain abscesses

Runjun Kumar, MD, PhD, Baylor College of Medicine, Houston, TX, USA

Case Studies in Hematopathology

Molecular and histopathologic findings in a case of large B-cell lymphoma with IRF4 rearrangement

Farah El-Sharkway, MD, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

A Genetically Novel Mantle Cell Lymphoma

Ahmed Lazim, Temple University Hospital, Philadelphia, PA, USA

Incidental discovery of acute myeloid leukemia during liquid biopsy of a lung cancer patient

Dingani Nkosi, PhD, University of Rochester Medical Center, Rochester, NY, USA

Inadvertent allogeneic hematopoietic stem cell transplant from a lung allograft

Laura Schultz-Rogers, PhD, University of North Carolina Chapel Hill Hospital, Chapel Hill, NC, USA

Clinical Whole Genome Sequencing Characterizes an Unusual Case of B-lymphoblastic Leukemia/Lymphoma

Brooj Abro, Washington University in St. Louis, St. Louis, MS, USA

Clonally Related Marginal Zone Lymphoma and Classic Hodgkin Lymphoma: A Rare Case Highlighting the Importance of IGK Rearrangement Testing

Bradley Drumheller, MD, Emory University Hospital, Atlanta, GA, USA

Case Studies in Infectious Diseases

Even if it looks like a ductal and walks like a ductal. . .

Jeremy Adler, University of  Chicago, Chicago, IL, USA

Case Studies in Solid Tumors

A rare case of CIC-rearranged sarcoma diagnosed with integrated RNA and DNA sequencing

Annie Garcia, MD, Baylor College of Medicine, Houston, TX, USA

Identification of identical BAP1 mutations in a patient’s peritoneal mesothelioma and mucosal melanoma: A precision medicine case study

Paul Zamiara, MD, Dalhousie University, Halifax, Nova Scotia, Canada

Clonal Evolution of Glioblastoma after Therapy

Tasos Gogakos, Mass General/Brigham Womens, Boston, MA, USA

A case series of FGFR3-KLF15 Fusion in Non-Small Cell Lung Cancer

Parsa Hodjat, Houston Methodist Hospital, Houston, TX, USA

Potentially Targetable FGFR2-INA Fusion in Intraductal Tubulopapillary Neoplasm of Pancreas (ITPN)

Irena Manukyan, Columbia University, New York, NY, USA